IMPROVING EXPRESSION OF PEPSINOGEN A FROM HOMO SAPIENS IN ASPERGILLUS NIGER BY USING A MULTI-COPY GENE KNOCK-IN STRATEGY

Pepsinogen A (PGA) plays an important role in the treatment of human gastrointestinal diseases.At present, PGA is mainly extracted from pig stomach, so its source is very limited and its price is very expensive.Production of PGA by microbial fermentation using an engineered strain with high PGA yield would be an ideal solution.This paper presents a

Pangkalpinang is the capital of Bangka Belitung Province by occupied most Melayu people with a rich culture.There are a number of cultures Pangkalpinang public relates to context learning mathematics.However, not many of the teachers in Pangkalpinang apply culture in learning mathematics.Whereas culture can be a starting point in learning mathemati